Abstract: In recent years, the destruction of the ozone layer has led to the enhancement of ultraviolet-B (UV-B) radiation, especially in plateaus, oceans and polar regions, due to the extremely high reflectivity of UV-B, which makes special occupational groups such as welders and ultraviolet disinfection workers face a higher risk of ultraviolet eye disease. To reduce the occurrence of eye diseases, physical protection can include using protective eyewear that meets the UV400 standard. In clinical treatment, options may include anti-inflammatory, anti-infection, surface anesthesia, and wound healing-promoting medications. In addition, natural active substances such as flavonoids, saponins, peptides and phenolic compounds have a good protection effect against UV-B radiation and can also be potential candidates for the research and development of related drugs.(Int Rev Ophthalmol, 2024, 48: 378-384)

Key words: UVB light, ultraviolet eye disease, natural products